In the past 200 years, cheaper weapon solutions have staged a comeback and even become dominant. Expect to see slug weaponry and railguns; expect to see single-shot hard-hitting "blaster muskets"; expect to see "pulse blasters" that consume blaster ammunition cells; expect to see a fair amount of melee weaponry wherever people can get away with it.
In the tight confines of a starship boarding operation, where hull breach is an annoying thing to have happen, the average distance between you and your opponent is going to be 5 meters or so, quickly closing to point blank range if you charge. Melee time.
A lot of this is covered in the Code subforum (the section on starship weaponry explains the thematic reasons for the emergence of new weapon systems). Quick summary: there will be major differences, most of which involve more limited weaponry, making superb, very powerful weapons fairly rare and/or expensive to operate.